The lovely ladies from Fifth Harmony will take home #1 honors this week as "Work From Home" (SYCO) ascends to the top, powered by Team Epic. The Chainsmokers' "Don't Let Me Down" f/Daya (Distruptor/Columbia) will move up to #3. Once again, this week's Greatest Gainer is Justin Timberlake's "Can't Stop The Feeling" (RCA) which explodes to #4—and that's before this upcoming "holiday mix weekend" programming kicks in even more spin momentum for him. Calvin Harris' "This Is What You Came For" f/Rihanna joins the Top 10 and will benefit from that holiday dynamic as well. Meanwhile RCA's Sia takes a big jump all the way up to #19 with "Cheap Thrills," while label mate Grace joins the Top 20 with "You Don't Own Me f/G-Eazy (Regime Music). Meghan Trainor's "Me Too" (Epic) takes a huge leap by climbing to #23 and Kent Jones' "Don't Mind" (WeTheBest/Epic) joins the Top 30. Charting this week will be Adele's "Send My Love (To Your New Lover)" (XL/Columbia) and DNCE's "Toothbrush" (Republic).